Loss of ING4 enhances hematopoietic regeneration in multipotent progenitor cells.
Despite its critical role in survival, many aspects of hematopoiesis remain unresolved.In the classical model of the hematopoietic program, quiescent hematopoietic stem Spoons cells (HSCs) sit at the top of the hematopoietic hierarchy, with the ability to self-renew and differentiate as needed.HSCs give rise to more proliferative progenitor cells,